Posted tagged ‘reflux’

Is burping really necessary? Grandma versus science!

August 22, 2016

The Pediatric Insider

© 2016 Roy Benaroch, MD

Ann wrote in: “My baby doesn’t burp easily – sometimes she doesn’t burp at all. Trying to make her burp makes her upset. Do babies really need to be burped after nursing?”

A fair question. Generations of parents have been burping their babies, and it seems like something we probably ought to do. I mean, it’s uncomfortable to have un-burped gas in your belly, right? And gas there probably causes fussiness, and maybe makes babies spit up, right? Not only does it make sense, but that’s what Grandma has been saying. Could Grandma possibly be wrong?

Let’s see what science says. There was a study of this exact question, published in 2014 in the journal Child: Care, Health and Development. A group including nursing and pediatric specialists from Chandigarh, India took on the Grandmas in their publication, “A randomized controlled trial of burping for the prevention of colic and regurgitation in healthy infants.” Their conclusion: “burping did not significantly lower colic events and there was significant increase in regurgitation episodes.” Yikes!

It was a simple study design, the kind I like best. 71 babies were randomly placed into two groups: an “intervention” group, where moms were taught burping techniques and told to burp their babies after meals; and a “control” group, where mom were taught other things about parenting, but were not taught about burping. The babies were all otherwise healthy, ordinary term infants, enrolled shortly after birth. They were followed for three months, with the families recording crying times and the number of spit-ups (regurgitation.)

The results: the amount of crying in each group was about the same. Burping did not prevent “colic”, or excessive crying. When comparing the episodes of spit-up, the “burping” group had approximately twice as many spit up episodes as the non-burped babies. So: burping had no effect on crying, and actually made spitting worse.

There are some important limitations. The study was done in India, and the conclusions might not be the same in babies from other parts of the world. Also, the intervention wasn’t “blinded” – for practical reasons, the parents knew if their babies were in the burping group. Still, the conclusions were statistically strong, and I think they’re probably correct.

Will this convince anyone to stop burping babies? Probably not. But I would say, for Ann, if burping makes your baby upset, there’s no reason to keep doing it. For the rest of you: you’ll have to settle this with Grandma, yourselves. I’m not getting in the middle of it!

Ogre belches are the worst

Reflux and babies: Ineffective treatment of a non-disease?

June 6, 2016

The Pediatric Insider

© 2016 Roy Benaroch, MD

Heather wrote in:

As a postpartum doula for the last 12 years I have seen something in the last couple of years that I would love your insight on. At least 30-40% of all the babies I care for now have reflux/GERD diagnosed. Roughly 25-30% are on daily meds for this. Parents go to the DR to get some sort of help for fussy babies and take home a prescription for GERD. Reminds me of when my kids were little and we got RX for antibiotics for so many things.

Heather’s right. Reflux (or GERD, gastroesophageal reflux disease) has emerged as a modern boogeyman, blamed for all sorts of symptoms in babies. The bottom line: most babies thought to have GERD don’t have it, and even among babies who do have GERD the medications used to treat it don’t seem to work.

Some background: “gastroesophageal reflux”, abbreviated GER, is the involuntary expulsion of stomach contents up into the esophagus. Stuff comes back up. All babies, and this is no surprise to parents, spit up, and most of them are perfectly happy to do it. Those “happy spitters” are easy to identify – they have no symptoms at all, no fussiness, they’re gaining weight, everyone is comfortable – and there’s really no controversy that these babies with “GER” need no treatment.

But there’s another abbreviation, GERD, for “gastroesophageal reflux DISEASE”, and that’s when things get murky. GERD = GER + D, or reflux that’s causing symptoms or problems. We’ve thought, for instance, that reflux could cause babies to be in pain. That makes sense, because many adults experience heartburn pain when they reflux. Though babies have less stomach acid than adults, they have some, and you’d think at least some of them might develop pain and inflammation in the esophagus from acid splashing up there. There are other symptoms, too, that have been blamed on GERD, like breathing problems or poor growth. And these do happen – GERD is a real thing.

Problem is, when it comes down to objective testing, it’s very difficult to tell whether GER is really causing the D in an individual patient. Yes, Junior is spitting – we can see that, it’s on the floor and all over dad’s shirt. And yes, Junior is fussy. But does one really cause the other? Does treating GER really help the symptoms we’re blaming on the reflux?

A study from the April, 2016 edition of the Journal of Pediatric Gastroenterology and Nutrition tried to help figure this out. They used a state-of-the-art diagnostic tool, a multichannel intraluminal impedance study, on 58 infants suspected of having GERD. Most of these babies had irritability as their main symptom. Of the 58 babies, only 10% ended up having an abnormal study – only 10% actually had reflux. And, among the babies who had episodes of irritability during the study itself, only about 20% had reflux during their symptoms. Reflux, when measured objectively, is uncommon even in babies who have symptoms we think of as reflux-related. And even during the symptoms, reflux usually isn’t occurring.

Do GERD medications, which primarily work by blocking acid secretion, even work in babies? The evidence, as reviewed by Jay Hochman in his pediatric GI blog,  says “no.”

It’s a conundrum. My gut feeling (ha!) is that GERD really does occur in some babies – but not often, and certainly not in most babies evaluated for fussiness. And if there isn’t GERD in the first place, of course the medicines for GERD aren’t going to help. There’s a strong placebo response rate in GERD studies of infants, so maybe to some degree an expectation of relief helps parents deal better with their babies’ fussiness. Or maybe the meds do work in the real cases of GERD, if diagnosed correctly in the first place. It’s just hard to separate all of this out, because the symptoms are so common. And those little babies don’t talk yet, so we don’t really know if they’re in pain, or where the pain is coming from.

Babies with excessive fussiness need a medical evaluation. Some, but not most, will have a specific medical explanation for their crying, and sometimes treatment helps. Many have more of a temperamental or developmental fussiness, and need to be held, and need reassured parents with backup support and a few good nights of rest to catch their breath. Medications aren’t always – or even usually – the answer.

Little. Purple. Different?

Reflux and bones

August 19, 2008

Just last week I published an article on gastroesophageal reflux (often abbreviated “GERD”). I wrote “All of these medications for GERD are really quite safe, which may be one reason why so many physicians use them indiscriminately for children who probably don’t even have reflux disease.”

Well, I think I missed the boat on this one. (more…)

Sneaky reflux

August 14, 2008

Allison asked, “My 4 year old was just diagnosed by an ENT (via rigid scope) with reflux and needs Prevacid to control it (Prilosec didn’t help). Otherwise, his voice is quite hoarse. If not for the hoarse voice, we would never have known he had it. Why would a 4 year old have reflux and is it something we should be seeing a GI doctor for?”

Reflux is both one of the most over-diagnosed and one of the most under-diagnosed conditions in pediatrics. That’s right: the same disease that’s diagnosed far too often in some children is at other times very sneaky and easy to overlook. (more…)